Though there is a prerequisite of physical training that includes perfecting a meditative wakefulness wherein the mind rests in perfect calm awareness, it is a skill that can be learned by anyone. It also allows for the Sisters to control pitch and "selected tone shadings" within their vocal register to trigger obedience receptors in others. RELATED: Dune Part 2: What Happens Next in the Novel - and What to Expect in the Sequel A fully capable Bene Gesserit can instruct every cell of her body with micro specificity, up to and including determining the sex of a fetus that is growing within her womb, a vital component of their secret agenda. Like the Guild and a handful of other organizations or powerful individuals, the Sisterhood also uses the spice to similarly enhance their minds and the advancements they've made with their bodies are byproducts of those enhancements. What Does the Dune Voice Actually Do - and Are There Other Powers? Ultimately, their goal is to produce a perfectly evolved male capable of being all places at once, possessing perfect knowledge of the past and visions of the future, with the mandate of shepherding the next era of humanity into a prophesied golden age. Unknown to their powerful allies however, the Sisterhood is loyal only to themselves and the culmination of a breeding program funneled through tens of thousands of human generations.
The Bene Gesserit serve as advisors to these powers, or Great Houses, in a spiritual and diplomatic capacity. This has created a galactic empire ruled by an Emperor and governed by regional feudal powers. The spice, among other things, heightens mental acuity and enables the Guild's navigators to chart incomprehensible distances with infinite variables and perfect accuracy.
The historical context of Dune takes place 20,000 years in Earth's future, wherein man has conquered the means of intergalactic travel, made possible by the Spacing Guild's technological monopoly, which is made possible due to their addiction to the spice melange.
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